Whereas low-rely MBL rarely progresses to CLL, substantial-depend MBL progresses to CLL necessitating therapy at a charge of one% to two% per annum. Substantial-rely MBL is distinguished from Rai 0 CLL dependant on if the B-mobile rely is previously mentioned or down below five × 109/L. While people today with the two high-count MBL and CLL Rai st